DREPANOCITOSIS PEDIATRIA PDF

Dayana V. Di Nuzzo I ; Silvana F. Fonseca II. I Pediatra.

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The Spanish Association of Pediatrics has as one of its main objectives the dissemination of rigorous and updated scientific information on the different areas of pediatrics. Annals of Pediatrics is the Body of Scientific Expression of the Association and is the vehicle through which members communicate. The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two receding years.

CiteScore measures average citations received per document published. Read more. SRJ is a prestige metric based on the idea that not all citations are the same. SJR uses a similar algorithm as the Google page rank; it provides a quantitative and qualitative measure of the journal's impact. SNIP measures contextual citation impact by wighting citations based on the total number of citations in a subject field. Con motivo de los flujos migratorios la drepanocitosis es una enfermedad emergente en nuestro medio..

Sickle cell anemia is a structural hemoglobinopathy inwhich morphological and physical changes in erythrocytescause vaso-occlusive episodes in various organs andtissues. The disease is common among blacks and theAfrican population. As a result of the growing migratoryflow, this is an emerging disease in Spain.

To present the casuistics of a pediatric hospital: clinicalonset, the most frequent features and complications, andtreatment. We performed a retrospective study of 22 patients agedless than 18 years old diagnosed with sickle cell anemiabetween January and December Epidemiologicdata, symptoms, complications, blood test results, treatment,and response were recorded.

The mean age of the patients was 39 months. No differenceswere found in sex. The most frequent complications were in-fections and Twenty-eight percentof the patients diagnosed before the age of 2 years presentedcomplications. Eleven patients received hydroxyureafor recurrent vaso-occlusive crises with favorableresults; one patient underwent splenectomy and anotherreceived an allogenic bone marrow transplant from anHLA-identical brother with excellent results..

This study reproduces the data described in the literaturefrom countries with a high prevalence of the disease.

Morbidity could be minimized by early diagnosis and preventivetreatment and good healthcare. Given the increasingincidence of the disease, screening of black andAfrican neonates and genetic counseling are recommendedtogether with guidelines for prompt and appropriatetreatment in primary health centers and emergency departments. ISSN: Previous article Next article.

Issue 2. Pages 01 February Sickle cell anemia: experience in a center. Download PDF. Corresponding author. This item has received. Article information.

Con motivo de los flujos migratorios la drepanocitosis es una enfermedad emergente en nuestro medio. Palabras clave:. Background Sickle cell anemia is a structural hemoglobinopathy inwhich morphological and physical changes in erythrocytescause vaso-occlusive episodes in various organs andtissues.

As a result of the growing migratoryflow, this is an emerging disease in Spain Objective To present the casuistics of a pediatric hospital: clinicalonset, the most frequent features and complications, andtreatment Material and methods We performed a retrospective study of 22 patients agedless than 18 years old diagnosed with sickle cell anemiabetween January and December Epidemiologicdata, symptoms, complications, blood test results, treatment,and response were recorded Results The mean age of the patients was 39 months.

Eleven patients received hydroxyureafor recurrent vaso-occlusive crises with favorableresults; one patient underwent splenectomy and anotherreceived an allogenic bone marrow transplant from anHLA-identical brother with excellent results. Conclusions This study reproduces the data described in the literaturefrom countries with a high prevalence of the disease. Key words:. Sickle-cell disease. Full text is only aviable in PDF. Rosse, M. Narla, L. Petz, M. New views of sickle cell disease pathophysiology and treatment.

Hematology, 42 , pp. Yaster, S. Kost-Byerly, L. The management of pain in sickle cell disease. Pediatr Clin North Am, 47 , pp. Platt, B. Thorington, D. Brambilla, P. Milner, W. Rosse, E. Pain in sickle cell disease: Rates and risk factors. N Engl J Med, , pp. Quinn, G. The acute chest syndrome of sickle cell disease. J Pediatr, , pp. Miller, E. Wright, M. Abboud, B. Berman, B. Files, C. Impact of chronic transfusion on incidence of pain and acute chest syndrome during the stroke prevention trial STOP in sickle cell anemia.

Pediatrics, , pp. Pediatrics, 10 , pp. Miller, L. Sleeper, C. Pegelow, L. Enos, W. Wang, S. Prediction of adverse outcomes in children with sickle cell disease.

Adams, K. Ohene-Frempong, W. Hematology, 41 , pp. Macklin, C. Pegelow, T. Kinney, L. Sleeper, J. Silent infarction as a risk factor for overt stroke in children with sickle cell anemia: A report from the cooperative study of sickle cell disease. J Pediatrics, , pp. Ware, S. Hydroxyurea as an alternative to blood transfusions for the prevention of recurrent stroke in children with sickle cell disease.

Blood, 94 , pp. Wang, L. Enos, D. Gallagher, R. Thompson, L. Guarini, E. Neuropsychologic performance in school-aged children with sickle cell disease: A report from the cooperative study of sickle cell disease. Adams, V. Mckie, L. Hsu, B. Files, E. Vichinsky, C. Prevention of a first stroke by transfusion in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography.

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The Spanish Association of Pediatrics has as one of its main objectives the dissemination of rigorous and updated scientific information on the different areas of pediatrics. Annals of Pediatrics is the Body of Scientific Expression of the Association and is the vehicle through which members communicate. The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two receding years. CiteScore measures average citations received per document published.

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The Spanish Association of Pediatrics has as one of its main objectives the dissemination of rigorous and updated scientific information on the different areas of pediatrics. Annals of Pediatrics is the Body of Scientific Expression of the Association and is the vehicle through which members communicate. The Impact Factor measures the average number of citations received in a particular year by papers published in the journal during the two receding years. CiteScore measures average citations received per document published. Read more. SRJ is a prestige metric based on the idea that not all citations are the same.

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